search for


Change of Pain Threshold and Nociceptive Flexion Reflex of Hyperalgesia Rat by High Voltage Pulsed Current
J Kor Soc Phys Ther 2006;18(2):25-34
Published online April 25, 2006
© 2006 The Korean Society of Physical Therapy.

Su-Hyon Kim, PT, MS; Dal-Ju Moon, PT, MS; Sug-Ju Choi, PT, PhD; Dae-In Jung, PT, PhD; Jung-Woo Lee, PT, MS; Jin-Gyu Jeong, PT, PhD; Tae-Youl Kim, PT, PhD

Department of Physical Therapy, Gokseong factory, Kumhotire co. inc; Department of Physical Therapy, Suncheon Hyoja Hospital; Department of Physical Therapy, Taegu Science Collge; Department of Physical Therapy, Cho sang-gu Surgery; Department of Physical Therapy, Graduate School, Dongshin University; Department of Physical Therapy, Chunnam Techno College; Department of Physical therapy, Dongshin University
Purpose: This study conducted quantitative sensory test and nociceptive flexion reflex(NFR) measurement to examine degree of pain depending on polarity of high voltage pulsed current(HVPC) of hyperalgesia site in hyperalgesia rat by local thermal injury. mechanical pain threshold, thermal pain threshold and root mean square of NFR were measured. Methods: This study was conducted with control group Ⅰ of hyperalgesia rat at hind paw by thermal injury and experimental groups divided into cathodal HVPC group Ⅱ, anodal HVPC group Ⅲ and alternate HVPC group Ⅳ. It measured pain threshold and root mean square(RMS) of NFR and obtained the following results. Results: Mechanical pain threshold of hyperalgeisa site was significantly increased at groups Ⅱ, Ⅲ and Ⅳ applying HVPC group compared to control group, but there was no difference among HVPC groups. Thermal pain threshold of hyperalgesia site showed a significant increase in group Ⅱ. Group Ⅲ showed significant difference after 4 days of hyperalgesia. RMS of NFR at hyperalgeisa site was significantly reduced in group Ⅱ after 2 days of hyperalgesia. Group Ⅲ showed significant decrease after 5 and 6 days of hyperalgesia. Conclusion: Consequently it was found that application of HVPC of hyperalgesia site increased pain threshold at hyperalgesia site by mechanical stimuli and thermal stimuli. NFR by electrical stimuli was similar to pain threshold by mechanical stimuli. Effects by polarity of HVPC showed the greatest reduction of hyperalgesia when cathodal electrode was used.
Keywords : Hyperalgesia, High voltage pulsed current, Quantitative sensory test, Nociceptive flexion reflex

December 2023, 35 (6)
Full Text(PDF) Free

Social Network Service

Cited By Articles
  • CrossRef (0)